How Does CBD Work?
Cannabinoids (CBD) affect the body in a variety of ways, and as medical studies unfold to support the benefits we've heard about for years, we are finding that CBD is a powerful and chemically effective way to pursue health and wellness. Research is showing us that CBD affects our bodies in a variety of ways, from our physiological systems down to cellular function and signaling molecules that are released by immune cells.
About the endocannabinoid system: Our body naturally produces Cannabinoids (CBD) that are perfectly received by our endocannabinoid system, one of the largest receptor networks in the body that helps to regulate chemical and electrical communication. When ingesting CBD, additional plant based cannabinoids are not only received by the ECS, but nourish the body's natural ability to produce more of its own cannabinoids (CBD). There are two types of CBD receptors: CB1 and CB2 receptors. CB1 receptors are in the brain and regulate movement, coordination, pain, emotions, mood, appetite, thought processing, and memory. CB2 receptors affect the immune system, inflammation and pain levels.
About the endocannabinoid system: Our body naturally produces Cannabinoids (CBD) that are perfectly received by our endocannabinoid system, one of the largest receptor networks in the body that helps to regulate chemical and electrical communication. When ingesting CBD, additional plant based cannabinoids are not only received by the ECS, but nourish the body's natural ability to produce more of its own cannabinoids (CBD). There are two types of CBD receptors: CB1 and CB2 receptors. CB1 receptors are in the brain and regulate movement, coordination, pain, emotions, mood, appetite, thought processing, and memory. CB2 receptors affect the immune system, inflammation and pain levels.
"HERBALISM IS SUCH AN INCREDIBLE PRACTICE. THE FACT THAT WE CAN FIND THE PUZZLE PIECES TO OUR HEALTH GROWING DIRECTLY FROM OUR EARTH IS CONSISTENTLY ENLIGHTENING, ESPECIALLY AS RESEARCH CATCHES UP. PHARMACEUTICAL MEDICATIONS, BY DESIGN, ORIGINATE WITH THE DESIRE TO MASS PRODUCE THE EXACT SAME CHEMICAL MAKEUP OF PLANTS. WE SEE WITH CANNABIS AND HEMP THAT THE BENEFITS ARE ENDLESS, FROM HEALTH IMPROVEMENTS TO SUSTAINABLE WAYS TO CREATE CLOTHING, PAPER, ROPE AND HUNDREDS Of OTHER PRODUCTS THAT CAN BOOST OUR ECONOMY AND HELP US SAVE THE EARTH. IT'S AS IF THIS PLANT FAMILY WAS DIVINELY CREATED... SPECIFICALLY FOR US."
-KATHLEEN J KWESKIN LMT RYT, CEO & FOUNDER OF GROW WELLNESS
-KATHLEEN J KWESKIN LMT RYT, CEO & FOUNDER OF GROW WELLNESS
Benefits of CBD
- Natural pain relief properties
- Helps to reduce inflammation
- Relieves symptoms of addiction
- Reduces anxiety, depression and paranoia
- Improves quality of sleep
- FDA approved for seizure disorders
- Treats symptoms of acne
- Positive effect on Diabetes
- Positive effects in the treatment of Alzheimer's Disease
- Positive effects in the treatment of Cancer and tumor
Methods of CBD Use
- Tinctures - Sublingual, regular intake of CBD is one of the most direct and effective ways to experience CBD.
- Topicals - CBD is infused into salves, creams, bath bombs and more to address pain and inflammation in your bath-care routine.
- Edibles - A fun and tasty way to integrate CBD benefits into your life. You can find almost any food infused with CBD today, such as honey, gummies, chocolate and even drinks!
Where to begin
With a saturated and unregulated market, it is important to research the company where you decide to purchase your CBD. CBD providers should have Certificates of Analysis for all of their products, demonstrating the composition and integrity of the CBD they use.
Calculating your daily serving size: Everyone's body chemistry will process CBD a little differently. So, begin with a low, conservative serving size and then increase or decrease your serving size from there depending on your preference. A general rule of thumb to calculate your service size in milligrams is to divide your body weight by 4, and the resulting number is a great place to start.
Ex. Someone who weighs 140lb will begin with a daily serving size of 35 MG
When using CBD for anxiety, depression, inflammation, or chronic pain, take half of your daily serving in the morning and half in the afternoon.
When using CBD for restful sleep, take the full serving size before bed.
Where to buy CBD: Grow Wellness Therapeutic SHOP
Calculating your daily serving size: Everyone's body chemistry will process CBD a little differently. So, begin with a low, conservative serving size and then increase or decrease your serving size from there depending on your preference. A general rule of thumb to calculate your service size in milligrams is to divide your body weight by 4, and the resulting number is a great place to start.
Ex. Someone who weighs 140lb will begin with a daily serving size of 35 MG
When using CBD for anxiety, depression, inflammation, or chronic pain, take half of your daily serving in the morning and half in the afternoon.
When using CBD for restful sleep, take the full serving size before bed.
Where to buy CBD: Grow Wellness Therapeutic SHOP
What makes our cbd different
When the owner of Grow Wellness visited her home state of New Mexico, she found immense relief from neck pain and anxiety using a CBD salve and CBD edibles. Upon returning home, she began to recommend CBD to her patients and yoga students, but found that the market was saturated with unregulated products and that clients were not getting the best results possible.
So, she connected with renowned cannabis and hemp educators in the Southwest and was able to bring high quality, triple tested CBD products to the shelves of Grow Wellness; becoming one of the first massage therapists in the state to offer CBD options during massage sessions. Grow Wellness has always been on the front lines of the CBD and Cannabis movements, continuing the fight to break the stigma and normalize natural herbalism in its many forms.
Choosing Grow Wellness for your CBD products means choosing quality assurance, educated selections, and a wellness provider you know you can trust.
So, she connected with renowned cannabis and hemp educators in the Southwest and was able to bring high quality, triple tested CBD products to the shelves of Grow Wellness; becoming one of the first massage therapists in the state to offer CBD options during massage sessions. Grow Wellness has always been on the front lines of the CBD and Cannabis movements, continuing the fight to break the stigma and normalize natural herbalism in its many forms.
Choosing Grow Wellness for your CBD products means choosing quality assurance, educated selections, and a wellness provider you know you can trust.
LEARN MORE
Make sure to check out the articles we've gathered below to dive deeper into the research behind CBD and cannabis. Knowledge is power!
Want to get involved in the Cannabis industry? Listen to this podcast with cannabis educator and our founder's sister, Shanon Jaramillo! Gain a national outlook on cannabis jobs and hiring and figure out your timing around the new industry as a consumer, employee or a new business owner! Join the Cannabis Training Center HERE
Want to get involved in the Cannabis industry? Listen to this podcast with cannabis educator and our founder's sister, Shanon Jaramillo! Gain a national outlook on cannabis jobs and hiring and figure out your timing around the new industry as a consumer, employee or a new business owner! Join the Cannabis Training Center HERE
Research articles on the effectiveness of CBD
Endocannabinoid System Research
-Lutz, B et al. The endocannabinoid system in guarding against fear, anxiety and stress. Nat Rev Neurosci. 2015;16(12):705‐718.
-Hillard C. J. Stress regulates endocannabinoid-CB1 receptor signaling. Seminars in immunology, 26(5), 2014, 380–388
GI disorders and inflammatory bowel diseases
-Massa, F, and K Monory. “Endocannabinoids and the gastrointestinal tract.” Journal of endocrinological investigation vol. 29,3 Suppl (2006): 47-57.
Inflammation
-Burstein, Sumner. “Cannabidiol (CBD) and its analogs: a review of their effects on inflammation.” Bioorganic & medicinal chemistry vol. 23,7 (2015):
-Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S. and Corsi, L., 2020. "Cannabis Sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry And Role Against Oxidative Stress, Inflammation, And Cancer." Biomed Research International
Analgesic Properties- Pain Relief
-Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S. and Corsi, L., 2020. "Cannabis Sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry And Role Against Oxidative Stress, Inflammation, And Cancer."Biomed Research International
-Teitelbaum, Jacob. “A Hemp oil, CBD, and Marijuana Primer: Powerful Pain, Insomnia, and Anxiety-relieving Tools!.” Alternative therapies in health and medicine vol. 25,S2 (2019): 21-23.
Mental Health- Anxiety, depression, ptsd, substance abuse
-Zieba, Jerzy et al. “Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP-independent mechanism.” Pharmacology, biochemistry, and behavior vol. 181 (2019):
-Teitelbaum, Jacob. “A Hemp oil, CBD, and Marijuana Primer: Powerful Pain, Insomnia, and Anxiety-relieving Tools!.” Alternative therapies in health and medicine vol. 25,S2 (2019): 21-23.
-Shannon, Scott, and Janet Opila-Lehman. “Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.” The Permanente journal vol. 20,4 (2016):
-Crippa, José A et al. “Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.” Frontiers in immunology vol. 9 2009.
-Orsolini, Laura et al. “Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review.” Medicina (Kaunas, Lithuania) vol. 55,9 525. 23 Aug. 2019,
-Blessing, Esther M et al. “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics vol. 12,4 (2015):
-Shannon, Scott et al. “Cannabidiol in Anxiety and Sleep: A Large Case Series.” The Permanente journal vol. 23 (2019): 18-041.
Seizure Treatment & Brain Tumor Treatment
-Warren, P. and Bebin, M., 2020. "The Use Of Cannabidiol For Seizure Management In Patients With Brain Tumor-Related Epilepsy" Neurocase Journal- The Neural Basis of Cognition. Taylor & Francis. Available at: <https://www.tandfonline.com/doi/full/10.1080/13554794.2017.1391294>
-Tzadok, Michal et al. “CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience.” Seizure vol. 35 (2016)
-Hausman-Kedem, Moran et al. “Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents - An observational, longitudinal study.” Brain & development vol. 40,7 (2018)
Chronic Illness
-Crippa, José A et al. “Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.” Frontiers in immunology vol. 9 2009.
Insomnia and sleep disorders
-Shannon, Scott, and Janet Opila-Lehman. “Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.” The Permanente journal vol. 20,4 (2016):
Cancer Treatment
-M, P., J, G. and B, S., 2020. Cannabinoids - A New Weapon Against Cancer? National Library of Medicine. PubMed. Available at: <https://pubmed.ncbi.nlm.nih.gov/28100841/>
-Solinas, Marta et al. “Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.” PloS one vol. 8,10 National Library of Medicine.
-Yamada, Takahiro et al. “TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer.” Urology vol. 76,2 (2010) National Library of Medicine.
-Shrivastava, Ashutosh et al. “Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.” Molecular cancer therapeutics vol. 10,7 (2011).
-McAllister, Sean D et al. “Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.” Breast cancer research and treatment vol. 129,1 (2011): 37-47.
-Ligresti, Alessia et al. “Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.” The Journal of pharmacology and experimental therapeutics vol. 318,3 (2006)
-Ramer, Robert et al. “Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.” FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 26,4 (2012):
-Pacher, Pál. “Towards the use of non-psychoactive cannabinoids for prostate cancer.” British journal of pharmacology vol. 168,1 (2013)
-Adinolfi, Barbara et al. “Anticancer activity of anandamide in human cutaneous melanoma cells.” European journal of pharmacology vol. 718,1-3 (2013):
Tumor Treatment
-Massi, Paola et al. “Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.” The Journal of pharmacology and experimental therapeutics vol. 308,3 (2004):
Parkinson's Treatment
-Crippa, José Alexandre S et al. “Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms?.” European archives of psychiatry and clinical neuroscience vol. 269,1 (2019)
-Ferreira-Junior, Nilson C et al. “Biological bases for a possible effect of cannabidiol in Parkinson's disease.” Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) vol. 42,2 (2020): 218-224. doi:10.1590/1516-4446-2019-0460
-Lutz, B et al. The endocannabinoid system in guarding against fear, anxiety and stress. Nat Rev Neurosci. 2015;16(12):705‐718.
-Hillard C. J. Stress regulates endocannabinoid-CB1 receptor signaling. Seminars in immunology, 26(5), 2014, 380–388
GI disorders and inflammatory bowel diseases
-Massa, F, and K Monory. “Endocannabinoids and the gastrointestinal tract.” Journal of endocrinological investigation vol. 29,3 Suppl (2006): 47-57.
Inflammation
-Burstein, Sumner. “Cannabidiol (CBD) and its analogs: a review of their effects on inflammation.” Bioorganic & medicinal chemistry vol. 23,7 (2015):
-Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S. and Corsi, L., 2020. "Cannabis Sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry And Role Against Oxidative Stress, Inflammation, And Cancer." Biomed Research International
Analgesic Properties- Pain Relief
-Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S. and Corsi, L., 2020. "Cannabis Sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry And Role Against Oxidative Stress, Inflammation, And Cancer."Biomed Research International
-Teitelbaum, Jacob. “A Hemp oil, CBD, and Marijuana Primer: Powerful Pain, Insomnia, and Anxiety-relieving Tools!.” Alternative therapies in health and medicine vol. 25,S2 (2019): 21-23.
Mental Health- Anxiety, depression, ptsd, substance abuse
-Zieba, Jerzy et al. “Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP-independent mechanism.” Pharmacology, biochemistry, and behavior vol. 181 (2019):
-Teitelbaum, Jacob. “A Hemp oil, CBD, and Marijuana Primer: Powerful Pain, Insomnia, and Anxiety-relieving Tools!.” Alternative therapies in health and medicine vol. 25,S2 (2019): 21-23.
-Shannon, Scott, and Janet Opila-Lehman. “Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.” The Permanente journal vol. 20,4 (2016):
-Crippa, José A et al. “Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.” Frontiers in immunology vol. 9 2009.
-Orsolini, Laura et al. “Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review.” Medicina (Kaunas, Lithuania) vol. 55,9 525. 23 Aug. 2019,
-Blessing, Esther M et al. “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics vol. 12,4 (2015):
-Shannon, Scott et al. “Cannabidiol in Anxiety and Sleep: A Large Case Series.” The Permanente journal vol. 23 (2019): 18-041.
Seizure Treatment & Brain Tumor Treatment
-Warren, P. and Bebin, M., 2020. "The Use Of Cannabidiol For Seizure Management In Patients With Brain Tumor-Related Epilepsy" Neurocase Journal- The Neural Basis of Cognition. Taylor & Francis. Available at: <https://www.tandfonline.com/doi/full/10.1080/13554794.2017.1391294>
-Tzadok, Michal et al. “CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience.” Seizure vol. 35 (2016)
-Hausman-Kedem, Moran et al. “Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents - An observational, longitudinal study.” Brain & development vol. 40,7 (2018)
Chronic Illness
-Crippa, José A et al. “Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.” Frontiers in immunology vol. 9 2009.
Insomnia and sleep disorders
-Shannon, Scott, and Janet Opila-Lehman. “Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report.” The Permanente journal vol. 20,4 (2016):
Cancer Treatment
-M, P., J, G. and B, S., 2020. Cannabinoids - A New Weapon Against Cancer? National Library of Medicine. PubMed. Available at: <https://pubmed.ncbi.nlm.nih.gov/28100841/>
-Solinas, Marta et al. “Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.” PloS one vol. 8,10 National Library of Medicine.
-Yamada, Takahiro et al. “TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer.” Urology vol. 76,2 (2010) National Library of Medicine.
-Shrivastava, Ashutosh et al. “Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.” Molecular cancer therapeutics vol. 10,7 (2011).
-McAllister, Sean D et al. “Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis.” Breast cancer research and treatment vol. 129,1 (2011): 37-47.
-Ligresti, Alessia et al. “Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.” The Journal of pharmacology and experimental therapeutics vol. 318,3 (2006)
-Ramer, Robert et al. “Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.” FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 26,4 (2012):
-Pacher, Pál. “Towards the use of non-psychoactive cannabinoids for prostate cancer.” British journal of pharmacology vol. 168,1 (2013)
-Adinolfi, Barbara et al. “Anticancer activity of anandamide in human cutaneous melanoma cells.” European journal of pharmacology vol. 718,1-3 (2013):
Tumor Treatment
-Massi, Paola et al. “Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.” The Journal of pharmacology and experimental therapeutics vol. 308,3 (2004):
Parkinson's Treatment
-Crippa, José Alexandre S et al. “Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms?.” European archives of psychiatry and clinical neuroscience vol. 269,1 (2019)
-Ferreira-Junior, Nilson C et al. “Biological bases for a possible effect of cannabidiol in Parkinson's disease.” Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) vol. 42,2 (2020): 218-224. doi:10.1590/1516-4446-2019-0460